@Article{SiqueiraAMMBPCVT:2020:ViBiBi,
               author = "Siqueira, Idalia Aparecida Waltrick Brito and Amaral, Suelen 
                         Sim{\~o}es and Moura, Nayara Koba de and Machado, Jo{\~a}o Paulo 
                         Barros and Backes, Eduardo Henrique and Passador, F{\'a}bio 
                         Roberto and Camargo, Samira Esteves Afonso and Vasconcellos, Luana 
                         Marotta Reis de and Trich{\^e}s, Eliandra Sousa",
          affiliation = "{Universidade Federal de S{\~a}o Paulo (UNIFESP)} and 
                         {Universidade Estadual Paulista (UNESP)} and {Universidade Federal 
                         de S{\~a}o Paulo (UNIFESP)} and {Instituto Nacional de Pesquisas 
                         Espaciais (INPE)} and {Universidade Federal de S{\~a}o Carlos 
                         (UFSCar)} and {Universidade Federal de S{\~a}o Paulo (UNIFESP)} 
                         and {University of Florida (UFL)} and {Universidade Estadual 
                         Paulista (UNESP)} and {Universidade Federal de S{\~a}o Paulo 
                         (UNIFESP)}",
                title = "In vitro bioactivity and biological assays of porous membranes of 
                         the poly(lactic acid) containing calcium silicate fibers",
              journal = "Polymer Bulletin",
                 year = "2020",
               volume = "77",
               number = "10",
                pages = "5357--5371",
                month = "Oct.",
             keywords = "PLA, Porous polymeric membranes, Calcium silicate fbers, 
                         Bioactivity, SBF.",
             abstract = "A new approach in dentistry is based on the development of 
                         resorbable polymeric membranes for guided bone regeneration. The 
                         porous membrane surface promotes better cell adhesion and 
                         proliferation. Poly(lactic acid) (PLA) is one of most widely used 
                         polymers for several biological applications, with the advantage 
                         of presenting hydrolysis degradation and bioresorption of its 
                         products. In this work, PLA porous polymeric membranes containing 
                         calcium silicate (CaSiO3) fibers were prepared by controlled 
                         humidity technique. The porous membranes were characterized by 
                         scanning electron microscopy, X-ray diffraction, differential 
                         scanning calorimetry, bioactivity in simulated body fluid and 
                         biological studies in vitro. The incorporation of the CaSiO3 
                         fibers into the polymeric matrix increased the pore size (1.534.9 
                         µm). In the bioactivity assay, PLA/CASiO3 membranes induced the 
                         formation of a hydroxyapatite layer on the porous membrane 
                         surface. Also, in vitro biologic assays showed that the porous 
                         membranes provided suitable environment for cell attachment and 
                         proliferation.",
                  doi = "10.1007/s00289-019-03021-5",
                  url = "http://dx.doi.org/10.1007/s00289-019-03021-5",
                 issn = "0170-0839",
             language = "en",
           targetfile = "siqueira_in vitro.pdf",
        urlaccessdate = "28 abr. 2024"
}